‘Best Medicine’ Season 2 Is a Spoonful of Sugar
"This town is very strange. But we mean well."
Fox’s Best Medicine was one of 2025’s most unexpected TV delights, a fish-out-of-water comedy full of quirky, likable characters, and aggressively whimsical charm. A remake of the popular ITV series Doc Martin, which ran for ten seasons over two decades and achieved cult status here in America thanks to its regular broadcasts on local PBS stations, the show follows a talented surgeon with a blood phobia who finds his new perspective on his professional calling after he’s fired from a more prestigious big-city job.
Part cozy small-town drama, part slow-burn romance, and part medical case-of-the-week procedural, Best Medicine follows Dr. Martin Best (Josh Charles) as he returns to the coastal Maine town where he spent summers with his beloved Aunt Sarah (Annie Potts) as a child. Prickly and rather lacking in basic social skills, Martin initially finds Port Wenn’s aggressive friendliness and obsession with town-wide cultural festivals and events irritating. But even he can’t resist the town’s charm forever, and much of the show’s first outing is dedicated to Martin’s slow acceptance that maybe there really is a place for him among all these well-meaning weirdos.
Its second season doubles down on everything that made its first season so enjoyable. Bizarre medical cases, quirky town rivalries, deepening relationships, and more heartfelt lessons about the power of community and kindness fill the air. It’s silly, sweet, and fluffy, and thanks to the multitudinous Horrors found everywhere these days, its lighthearted appeal is just what the doctor ordered.
